Kaneka Awarded by The Society of Synthetic Organic Chemistry, Japan in 2018 for Innovative Process Development Utilizing Continuous Flow Reaction.

Kaneka Corporation (Headquarters: Minato-ku, Tokyo; President: Mamoru Kadokura) has been given the 2018 Technical Award of The Society of Synthetic Organic Chemistry*1, Japan for “Innovative process development of pharmaceutical products with continuous flow chemistry*2” in an award ceremony held on February 14, 2019 at Josui-Kaikan in Tokyo. This award is reserved for the persons who successfully display innovative research results leading to revolutionary impact in commercial organic chemical synthesis.

Kaneka has succeeded in the application of continuous flow chemistry to commercial pharmaceutical products and have designed and installed a customizable continuous flow reactor system that allows diversity of application through the ability to select the relevant reaction and reaction tube parameters. In addition, commercial production under GMP*3 conditions has already started utilizing this flow reactor, and this success has been recognized for this award.

In the field of small molecule pharmaceutical products, the recent demands have begun to trend toward an increased number of more diversified and smaller volume targets in the unmet medical needs. In response to this trend, Kaneka has focused on developing new applications of continuous flow chemistry at all scales for pharmaceutical products, including manufacturing facilities at Kaneka Singapore Co. (Pte) Ltd and Osaka Synthetic Chemical Laboratories, Inc.

We aim to expand our solution services in the Health Care business field utilizing this new capability of continuous flow chemistry, as well as enhancing capabilities for biopharmaceutical products.

1. Initially founded in 1942 by about four hundred members from military, government and the private sector with the aim to promote industrial applications of synthetic organic chemistry. The society was configured into its current form, and it has been a major contributor to the successful advancement of organic chemistry in Japan ever since. Now, membership is approximately 4,800.
2. The chemical reaction initiated continuously and successively in the reaction tube. This allows safer and easier operation for reactions including those which require difficult or dangerous conditions and it is expected that efficient pharmaceutical production can be enhanced by this technology.
3. Abbreviated name of Good Manufacturing Practice, the recommended guidelines and minimum requirements to ensure that products are consistently high in quality.